For nearing a few year/s now throughout CKD+IF ~ I am noticing an increased pattern of adverse symptoms when consuming oxalate heavy foods. Namely ~ lower mobility pains, flexibility limitations and overall feeling of lower-back encumbrances.
I'd like to share both a database and an online Oxalate consumption calculator (Globalrpx). This is worth mentioning ~ considering it handily calculates the overall footprint. You can find it here.
All you have to do is to set your checkboxes, # of serving/qty's next to each food item and the calculator will provide you an overall result and a rating.
They also have other calculators for convenience - BMI, TDEE (in various formats and formula methods), Protein intakes and (curiously) ~ an entire section dedicated to "Finances".
Endogenously, synthesis can occur as byproducts of general carbohydrate, protein (particularly from aminoacid Hydroxyproline) and fat breakdowns. Altogether, through what is known as Glyoxalate pathway, here the oxidative byproducts from macronutrients eventually form Glyoxylate, thought to be direct precursor to oxalate synthesis especially if it interacts with other known contributor(s) chiefly among them Ascorbic Acid.
Interesting to note that specific Vitamin deficiencies may also precipitate the above pathway. Namely - B1 and B6 deficiencies.
Next, the exogenous factors ~ from high dietary copper and oxalate rich foods.
Unfortunately due to copyright restrictions ~ copying and pasting even within benevolence intent is forbidden. I instead resort may only share following resources as URLs.
A good number of Youtube presentations are also plenty. Chief among them are as follows.
I may only speak from my own N=1. "Encumbrances", mobility concerns and/or "malaise" are what I clarify as:
All these indeed sounds minor. But over the years of cycling in and out of very high and very low amount of fibre intakes I can now attest with some degree of confidence that something will happen.
People of course remain free to opinionate my case be it "isolated", "anecdotal" and thus "unscientific". Be that as it may. But do not forget that you your"self" ~ remains an anecdote worthy for your own exploration.
I at times, have to partially wave goodbye; or at least greatly reduce consumptions of the following heavily suspect foods:
A note on coffees. There appears to be many conflicting and often confusing findings. TLDR; I have been coffee drinker for nearly as long as I have forgotten (at times ) about water. So far I do not think these have any serious impact on oxalate footprint.
I may only recommend you all to please read Sally K Norton's excellent coverage and lengthy self-meta on various reasons why the big discrepancies from one study after another. TLDR; instant coffees may possess higher amount than that of regular grounds.
Depending on the quantity of prior consumption and/or food types ~ I am confident to say that malaise or encumbrances may surface within a manner of hours. But on some clearly-suspect items, particularly black tea - as little as minutes upon ingestion.
If there are 24 hours urine test to examine possible kidney health, then such short window of insight ~ should indicate more than enough time for us all to test on our accord whether or not any suspecting food may have an effect.
Usually, abstinence usually resolve all symptoms within the same day or at least until one or two bowel movements. Other things that help mitigate include - regular mobility variations be it sit/stand stance. And obviously ~ regular training but within mindfulness especially if you are also suspected to have Ankylosing Spondylitis episodical flares ~ and/or suspected with disc degeneration.
Calcium and Magnesium both are chelators / thus binders with oxalates to prevent the inevitable crystalization in the kidney (Betz, M. 2022).
Coincidentally ~ Calcium salts (Huynh, H. et al 2020) and Magnesium (Massey, L. 2005) + (Riley, JM et al. 2013) appear to help offset the risk against hyper oxalate absorption. In particular, that latter study finds that acidic PH, tends to be synergistic with magnesium*. This also coincides with another study that looks at intestinal absorption suggesting that Mg absorption requires acidic medium, alongside a citrate (Schuchardt JH & Hahn A 2017).
*As per from the abstract: "Mg2+ inhibitory effect is synergistic with citrate and remains effective in acidic environments." (Riley, JM et al. 2013).
A pragmatic takeaway, were I to take for myself is to have both amino acid chelated version and the usual oxide version of Magnesium. These at least, allow the additional micros to be in favourable supply notably Vitamin B6 and manganese serving as methylation support and B6 in protein metabolism. As for Calcium, I still emphasize food sources from dairy for now, alongside my own DIY yoghurts. Once again, I would encourage you to please gather insight upon yourselves adequately first and foremost.
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I only speak from my own N=1 experience. Your's very own nutrigenomics and biology obviously will vary.
By no means I am condoning complete abstinence on all these foods. Many of these ~ namely cacao powders avocadoes, peanut butters still contain elusive and arguably essential minerals and anti-oxidants that are complimentary to everything else.
Irrespective oxalates should be a genuine concern. One must weigh the pros and cons with some personal introspect that at the very least no single food may yet ever be "safe".
My stance when it comes to bargaining with chaos have not changed cycle anything subjective. Years of SKD then Cyclical Keto + IF both indeed have taught me much.
Live-It-Forward,
AW.